NAD+

Essential cellular coenzyme studied in energy metabolism, mitochondrial function, DNA repair, and longevity research.

Cellular Energy Studies≥99% (HPLC verified) purity

$75.00

  • FormatLyophilized Powder / 500 mg
  • Storage-20°C for long-term stability

NAD+ is an essential coenzyme found in every living cell, where it supports many of the reactions involved in cellular energy production. It helps transfer…

50 in stock

NAD+$75.00
500+Enzymatic Reactions
7Sirtuin Enzymes
10Lots on Record
6Batch Assays
Overview

About NAD+

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in living cells and plays a central role in cellular energy metabolism. Research has examined NAD+ in mitochondrial function, electron transport, sirtuin activity, DNA repair, cellular signaling, and age-related metabolic changes.

Compound Information

Full Specification

Molecular FormulaC21H27N7O14P2 (CAS 53-84-9)
Molecular Weight663.43 g/mol
Purity≥99% (HPLC verified)
AppearanceWhite to off-white lyophilized powder
Storage-20°C for long-term stability
FormatLyophilized Powder / 500 mg
Molecular Structure

The NAD+ Molecule

An illustrative representation generated from the compound's molecular formula, alongside its logged molecular data. This figure is schematic — not a measured conformation.

Molecular Formula
C21H27N7O14P2 (CAS 53-84-9)
Molecular Weight663.43 g/mol
Sequence LengthSmall Molecule
CAS / ID53-84-9
Physical FormWhite to off-white lyophilized powder
Documented Purity≥99% (HPLC verified)
Use ClassResearch Use Only
How It Works

How NAD+ Works

The pathways NAD+ acts on — and what each one does. The animation traces its signal outward from the compound to every target it engages.

NAD+
Cellular Energy
NAD+-Dependent Signaling
DNA Repair

Signalling pathways studied in preclinical models · illustrative

Mitochondrial Function

Cellular Energy

NAD+ participates in mitochondrial electron transport and oxidative phosphorylation, supporting the conversion of nutrients into cellular energy.

Oxidative phosphorylationElectron transportATP production

Sirtuin Pathway

NAD+-Dependent Signaling

NAD+ serves as an obligate co-substrate for the seven sirtuin enzymes involved in cellular stress response, metabolic regulation, and aging-related research.

SIRT1–7Stress responseMetabolic signaling

PARP & Genomic Stability

DNA Repair

NAD+ is consumed by PARP enzymes during DNA repair processes and has been studied in relation to genomic stability and age-associated cellular changes.

PARP activityDNA repairGenomic stability
Uses & Applications

What NAD+ Is Researched For

Aging Biology

Aging & Senescence

Studied in model organisms in relation to lifespan, sirtuin pathway activity, mitochondrial function, and cellular aging.

Metabolic Research

Energy Metabolism

Studied in relation to cellular energy production, age-associated metabolic changes, and nuclear-mitochondrial communication.

Genomic Research

DNA Repair

Studied for its role as a substrate for PARP enzymes involved in DNA damage repair and genomic stability.

Mitochondrial Research

UPR Activation

Studied in relation to the mitochondrial unfolded protein response and cellular stress signaling.

Research Data

Study-Reported Magnitudes

Representative figures from published research; results vary by protocol.

NAD+ Decline by Age 50
50%
Mitochondrial Function Impact
85%
Sirtuin Activity Dependency
100%
DNA Repair Capacity
72%
FAQ

Common Questions About NAD+

What is NAD+?+

NAD+ (Nicotinamide Adenine Dinucleotide) is a cellular coenzyme involved in energy metabolism, electron transfer, enzymatic reactions, and cellular signaling.

Why is NAD+ important for cellular energy?+

NAD+ functions as an electron carrier in metabolic reactions and is involved in mitochondrial oxidative phosphorylation and cellular energy production.

How does NAD+ relate to aging research?+

NAD+ levels have been reported to decline with age across multiple tissue types, making NAD+ biology an area of study in aging and cellular senescence research.

What are sirtuins and why do they need NAD+?+

Sirtuins are a family of seven NAD+-dependent enzymes involved in research on cellular stress responses, metabolism, and aging biology.

What role does NAD+ play in DNA repair?+

NAD+ is consumed by PARP enzymes involved in DNA damage repair, and NAD+ availability has therefore been studied in relation to genomic stability.

How should NAD+ be stored?+

The supplied specification recommends storage at -20°C for long-term stability.