Semax

Synthetic ACTH(4-10) heptapeptide studied in BDNF signaling, cognitive function, neurotransmitter modulation, and neuroprotection research.

Neurotrophic Signaling Studies99.08% purity

$85.00

  • FormatLyophilized Powder / 10 mg
  • Storage-20°C for up to 24 months

Semax is a seven-amino-acid peptide originally developed by Russian researchers. Its structure includes a fragment derived from ACTH along with a short…

50 in stock

Semax$85.00
7Amino Acids
1.4×BDNF Fold Change
3Lots on Record
6Batch Assays
Overview

About Semax

Semax is a synthetic seven-amino-acid analog of ACTH(4-10). Preclinical research has examined Semax in relation to brain-derived neurotrophic factor (BDNF), neuronal survival, synaptic plasticity, serotonergic and dopaminergic signaling, cerebral ischemia, inflammatory pathways, and cognitive function. The supplied source also notes that the pharmaceutical formulation has been approved as a prescription nootropic in Russia; this research material is supplied for research use only.

Compound Information

Full Specification

Molecular FormulaC37H51N9O10S
Molecular Weight813.93 g/mol
Purity99.08%
AppearanceWhite to off-white lyophilized powder
Storage-20°C for up to 24 months
FormatLyophilized Powder / 10 mg
Molecular Structure

The Semax Molecule

An illustrative representation generated from the compound's molecular formula, alongside its logged molecular data. This figure is schematic — not a measured conformation.

Molecular Formula
C37H51N9O10S
Molecular Weight813.93 g/mol
Sequence Length7 residues
Physical FormWhite to off-white lyophilized powder
Documented Purity99.08%
Use ClassResearch Use Only
How It Works

How Semax Works

The pathways Semax acts on — and what each one does. The animation traces its signal outward from the compound to every target it engages.

Semax
Neurotrophic Signaling
Neurotransmitter Signaling
Neuroprotection

Signalling pathways studied in preclinical models · illustrative

BDNF Modulation

Neurotrophic Signaling

Semax has been studied in relation to BDNF expression, with levels up to 1.4-fold baseline measured in specific brain regions alongside neuronal survival and synaptic plasticity endpoints.

BDNFNeurotrophinsNeuronal survivalSynaptic plasticity

Serotonin & Dopamine Modulation

Neurotransmitter Signaling

Research has examined Semax in relation to serotonergic, dopaminergic, and noradrenergic systems involved in neurotransmitter signaling and cognitive processing.

SerotoninDopamineNoradrenalineCognitive signaling

Ischemic Models

Neuroprotection

Semax has been studied in cerebral ischemia models using infarct volume, inflammatory gene expression, neuronal survival, and oxidative-stress markers as research endpoints.

Cerebral ischemiaInfarct volumeNeuronal survivalOxidative stress
Uses & Applications

What Semax Is Researched For

Cognitive Research

Memory & Learning

Studied in animal models using cognitive function, memory consolidation, attention, and related behavioral endpoints.

Neuroprotection

Cerebral Ischemia Models

Studied in ischemic stroke models in relation to infarct volume, neuronal survival, inflammatory gene expression, and oxidative stress.

Neurotrophic Research

BDNF & Neurotrophin Signalling

Studied through BDNF and neurotrophin expression alongside neuronal plasticity and survival endpoints.

Immunology

Immune Modulation

Studied in relation to pro-inflammatory cytokines and oxidative-stress-related gene expression in experimental models.

Research Data

Study-Reported Magnitudes

Representative figures from published research; results vary by protocol.

BDNF Expression (fold change)
100%
Cognitive Performance (animal)
65%
Neuroprotection (ischemia)
78%
Anti-Inflammatory Effect
60%
FAQ

Common Questions About Semax

What is Semax and where does it come from?+

Semax is a synthetic seven-amino-acid analog of ACTH(4-10) developed at a Russian research institute. Its sequence is Met-Glu-His-Phe-Pro-Gly-Pro.

What has research shown about Semax?+

Preclinical research has examined Semax in relation to BDNF expression, neuronal survival, synaptic plasticity, serotonin and dopamine signaling, cerebral ischemia, inflammatory pathways, and cognitive function.

Is Semax FDA approved?+

The supplied source does not state that Semax is FDA approved. It states that the pharmaceutical formulation has been approved as a prescription nootropic in Russia since 2011. This material is supplied for research use only.

How does Semax differ from N-Acetyl Semax?+

The supplied source does not provide a specific comparison between Semax and N-Acetyl Semax.

How should Semax be stored?+

The supplied specification recommends storage at -20°C for up to 24 months.