KPV
α-MSH-derived tripeptide studied in NF-κB signaling, intestinal inflammation, epithelial repair, and antimicrobial research.
$55.00
- FormatLyophilized Powder / 10 mg
- Storage-20°C for long-term stability
KPV is a short tripeptide composed of lysine, proline, and valine. It is derived from the terminal portion of alpha-MSH and retains activity associated with…
50 in stock
About KPV
KPV is a three-amino-acid peptide consisting of lysine, proline, and valine and corresponds to the C-terminal tripeptide of α-MSH. Preclinical research has examined KPV in relation to NF-κB and MAP-kinase signaling, inflammatory cytokine output, PepT1-mediated cellular uptake, intestinal inflammation models, epithelial wound closure, and antimicrobial activity.
Full Specification
| Molecular Formula | C16H31N5O4 |
| Molecular Weight | 342.43 g/mol |
| Purity | ≥999.269 |
| Appearance | White to off-white lyophilized powder |
| Storage | -20°C for long-term stability |
| Format | Lyophilized Powder / 10 mg |
The KPV Molecule
An illustrative representation generated from the compound's molecular formula, alongside its logged molecular data. This figure is schematic — not a measured conformation.
How KPV Works
The pathways KPV acts on — and what each one does. The animation traces its signal outward from the compound to every target it engages.
Signalling pathways studied in preclinical models · illustrative
Inflammatory Pathway Suppression
NF-κB InhibitionKPV has been studied for effects on NF-κB and MAP-kinase signaling, with reduced inflammatory cytokine output measured in preclinical models.
Cellular Transport & Action
PepT1-Mediated UptakeResearch has examined KPV uptake through the PepT1 di/tripeptide transporter, enabling intracellular study of inflammatory signaling pathways.
Melanocortin Fragment
α-MSH-Derived ActivityKPV is the C-terminal tripeptide of α-MSH and has been studied for anti-inflammatory, immunomodulatory, and antimicrobial activity.
What KPV Is Researched For
Intestinal Inflammation Models
Studied in DSS- and TNBS-induced colitis models in relation to intestinal inflammatory responses.
α-MSH Anti-Inflammatory Signaling
Studied as the C-terminal tripeptide of α-MSH in relation to anti-inflammatory and immunomodulatory signaling.
Epithelial Wound Closure
Studied in epithelial repair models, including a rabbit corneal wound model.
Antimicrobial Activity
Studied for antimicrobial effects against organisms including Staphylococcus aureus and Candida albicans.
Study-Reported Magnitudes
Representative figures from published research; results vary by protocol.
Common Questions About KPV
KPV is a three-amino-acid peptide consisting of lysine, proline, and valine and corresponds to residues 11–13 of α-MSH.
KPV has been studied in preclinical models for effects on NF-κB and MAP-kinase signaling and inflammatory cytokine output.
PepT1 is a di- and tripeptide transporter expressed in intestinal epithelial and immune cells. Research has examined PepT1-mediated uptake as a route for KPV cellular entry.
KPV has been studied in DSS- and TNBS-induced colitis models, where researchers measured intestinal inflammation and disease severity.
The supplied source presents KPV research in preclinical models and does not provide evidence of human clinical testing.
The supplied specification recommends storage at -20°C for long-term stability.