Selank
GABAergic & Neurotrophic Signaling Studies
$55.00
- FormatLyophilized powder
- StorageStore lyophilized vial frozen; refer to COA for lot-specific stability data
50 in stock
About Selank
Selank is a synthetic peptide composed of seven amino acids and derived from tuftsin, a naturally occurring immunomodulatory peptide. Its structure includes the same stabilizing C-terminal sequence found in Semax, and both peptides were developed through research originating from the same Russian institute. In preclinical studies, Selank has been investigated for its effects on GABA-related signaling, an inhibitory system involved in regulating neural activity, as well as a range of stress-associated behavioral and physiological endpoints.
Full Specification
| Molecular Formula | C33H57N11O8 |
| Molecular Weight | 751.88 g/mol |
| Purity | ≥99% (HPLC verified) |
| Appearance | White to off-white lyophilized powder |
| Storage | Store lyophilized vial frozen; refer to COA for lot-specific stability data |
| Format | Lyophilized powder |
The Selank Molecule
An illustrative representation generated from the compound's molecular formula, alongside its logged molecular data. This figure is schematic — not a measured conformation.
How Selank Works
The pathways Selank acts on — and what each one does. The animation traces its signal outward from the compound to every target it engages.
Signalling pathways studied in preclinical models · illustrative
GABA-A Receptor Modulation
GABAergicSelank has been studied for its ability to influence GABAergic signaling, including GABA-A receptor activity and receptor-subunit expression. These pathways are closely involved in regulating inhibitory neurotransmission and stress-related responses.
BDNF & Enkephalin Regulation
NeurotrophicSelank has been associated with changes in BDNF expression and enkephalin metabolism, systems that contribute to neuroplasticity, synaptic function, and the regulation of mood- and cognition-related signaling.
Tuftsin-Derived Immune Modulation
ImmunomodulatoryDerived from the natural immune peptide tuftsin, Selank has been investigated for its effects on cytokine and interferon signaling, pathways involved in coordinating inflammatory and immune responses.
What Selank Is Researched For
Anxiety-Related Signaling
Studied in preclinical anxiety models, including elevated plus maze and open-field testing, with effects linked primarily to GABAergic neurotransmission.
Learning & Memory
Examined in animal models of stress-related cognitive impairment, focusing on learning and memory consolidation.
Cytokine & Immune Regulation
Investigated for its influence on cytokine and interferon signaling, including pathways involving IL-6 and TNF-α.
Transcriptomic Effects
Gene-expression studies have identified changes in pathways related to serotonin and dopamine metabolism, synaptic function, and neuroplasticity.
Common Questions About Selank
A synthetic seven-amino-acid peptide derived from tuftsin, a naturally occurring immunomodulatory peptide.
Both share the same stabilizing C-terminal sequence and originate from the same Russian institute, but are studied for different primary pathways.
GABAergic signaling, anxiety-related models, learning and memory, cytokine and interferon signaling, and gene-expression changes linked to neuroplasticity.