Tesamorelin
Synthetic GHRH(1-44) analog studied in growth hormone secretion, visceral adipose signaling, IGF-1 modulation, and GH-axis research.
$150.00
- FormatLyophilized Powder / 20 mg
- Storage-20°C for long-term stability
Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) that retains the full 44-amino-acid sequence of the naturally occurring human…
50 in stock
About Tesamorelin
Tesamorelin is a synthetic trans-3-hexenoic acid–modified analog of human growth hormone-releasing hormone (GHRH 1-44). Research has examined its interaction with GHRH receptors, endogenous growth hormone secretion, downstream IGF-1 signaling, visceral adipose tissue biology, body composition, and brain structure and function. Tesamorelin is also an approved pharmaceutical ingredient under the brand name Egrifta for a specific clinical indication; this research material is supplied for research use only.
Full Specification
| Molecular Formula | C221H366N72O67S |
| Molecular Weight | 5135.89 g/mol |
| Purity | ≥99% (HPLC verified) |
| Appearance | White to off-white lyophilized powder |
| Storage | -20°C for long-term stability |
| Format | Lyophilized Powder / 20 mg |
The Tesamorelin Molecule
An illustrative representation generated from the compound's molecular formula, alongside its logged molecular data. This figure is schematic — not a measured conformation.
How Tesamorelin Works
The pathways Tesamorelin acts on — and what each one does. The animation traces its signal outward from the compound to every target it engages.
Signalling pathways studied in preclinical models · illustrative
Growth Hormone Secretagogue
GHRH-R AgonismTesamorelin is a modified analog of human GHRH(1-44) that binds GHRH receptors and stimulates endogenous growth hormone secretion, with downstream IGF-1 production measured in research.
Visceral Adipose Signalling
LipolysisTesamorelin is studied in relation to GH-mediated signaling in visceral adipose tissue, including hormone-sensitive lipase activity and free-fatty-acid release.
Cognitive & Brain Research
NeuroprotectionResearch has examined tesamorelin in relation to brain structure and function through the GH/IGF-1 axis, including regional gray matter volume and functional connectivity.
What Tesamorelin Is Researched For
Visceral Fat & Body Composition
Studied in relation to GH-driven signaling in visceral adipose tissue and body-composition changes.
Brain Structure & Function
Studied through IGF-1 signaling in relation to regional brain volume, functional connectivity, and cognitive aging research.
GH/IGF-1 Axis
Used as a research model for GHRH receptor pharmacology, growth hormone secretion, and downstream IGF-1 modulation.
Lipid & Cardiovascular Markers
Research has examined triglycerides, non-HDL cholesterol, and carotid intima-media thickness in relation to GH-axis modulation.
Study-Reported Magnitudes
Representative figures from published research; results vary by protocol.
Common Questions About Tesamorelin
Tesamorelin is a synthetic modified analog of human GHRH(1-44) that stimulates the pituitary to release endogenous growth hormone. It is studied through the GHRH/GH/IGF-1 axis rather than functioning as directly administered growth hormone.
The supplied source states that tesamorelin was FDA approved in 2010 under the brand name Egrifta for HIV-associated lipodystrophy. This research material is supplied for research use only and is not the approved pharmaceutical product.
Tesamorelin is studied in relation to GH-mediated lipolytic signaling in visceral adipose tissue, including hormone-sensitive lipase activity, free-fatty-acid release, and changes in visceral fat.
Research has examined tesamorelin through the GH/IGF-1 axis in relation to regional brain structure, gray matter volume, functional connectivity, and cognitive aging.
The supplied source does not provide a complete safety profile for this research material. Researchers should consult the relevant scientific literature and applicable institutional safety procedures before use.
The supplied specification recommends storage at -20°C for long-term stability.