Retatrutide

Triple-Receptor Metabolic Studies

Metabolic Regulation Studies

Price range: $110.00 through $160.00

  • FormatLyophilized powder, single-use vial (10mg or 20mg)
  • StorageStore lyophilized vial frozen; refer to COA for lot-specific stability data

Retatrutide is the research designation used for LY3437943, a compound designed to activate three metabolic receptors simultaneously: GLP-1, GIP, and glucagon….

Retatrutide Price range: $110.00 through $160.00
Overview

About Retatrutide

Retatrutide is the research designation used for LY3437943, a compound designed to activate three metabolic receptors simultaneously: GLP-1, GIP, and glucagon. Research has explored its effects on metabolic activity, energy expenditure, and blood glucose regulation in study models. While many related compounds target one or two receptors, Retatrutide is distinguished by its triple-receptor activity.

Compound Information

Full Specification

Molecular FormulaC221H342N50O68
Molecular Weight4731.32 g/mol
AppearanceWhite to off-white lyophilized powder
StorageStore lyophilized vial frozen; refer to COA for lot-specific stability data
FormatLyophilized powder, single-use vial (10mg or 20mg)
Molecular Structure

The Retatrutide Molecule

An illustrative representation generated from the compound's molecular formula, alongside its logged molecular data. This figure is schematic — not a measured conformation.

Molecular Formula
C221H342N50O68
Molecular Weight4731.32 g/mol
CAS / ID2381089-83-2 (research designation LY3437943)
Physical FormWhite to off-white lyophilized powder
Use ClassResearch Use Only
How It Works

How Retatrutide Works

The pathways Retatrutide acts on — and what each one does. The animation traces its signal outward from the compound to every target it engages.

Retatrutide
Three Pathways, One Molecule
~6-Day Duration

Signalling pathways studied in preclinical models · illustrative

Simultaneous Receptor Engagement

Three Pathways, One Molecule

Activates GLP-1, GIP, and glucagon receptors at once rather than one or two targets, unlike earlier single- or dual-agonist compounds.

Triple receptor agonismGIP + GLP-1 + glucagon

Extended Systemic Half-Life

~6-Day Duration

C18 fatty-acid acylation is associated with an extended half-life of roughly 6 days in study models.

C18 acylationExtended half-life
Uses & Applications

What Retatrutide Is Researched For

Metabolic Research

Multi-Receptor Signaling

Studied for combined GLP-1/GIP/glucagon receptor activity.

Metabolic Research

Glucose & Energy Studies

Examined for effects on blood glucose regulation and energy expenditure.

Additional information

Weight

10mg, 20mg
FAQ

Common Questions About Retatrutide

What is Retatrutide?+

The research designation for LY3437943, a compound studied for simultaneous activity at GLP-1, GIP, and glucagon receptors.

What makes it different from single-receptor compounds?+

Its triple-receptor activity, versus compounds that target only one or two receptors.

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